42. Thomas Frist Jr., MD: $17 billion
Mr. Frist founded Hospital Corp. of America in 1968. HCA Healthcare owns and operates 187 hospitals and 2,000 care sites.
66. Carl Cook: $9.7 billion
Mr. Cook is CEO of medical device manufacturer Cook Group.
138. Reinhold Schmieding: $6.5 billion
Mr. Schmieding started orthopedic surgical tools company Arthrex in 1981 and still owns more than 90 percent of the company.
153. Ge Li: $6.1 billion
Mr. Li co-founded WuXi AppTec, a research and development and manufacturing company that supports biotech and pharmaceuticals.
160. Patrick Soon-Shiong, MD: $5.7 billion
Dr. Soon-Shiong was a practicing physician before inventing the cancer medication Abraxane. In 2016, he created a biotech startup. In 2018, he bought the Los Angeles Times and the San Diego Union-Tribune.
169. Ronda Stryker: $5.6 billion
Ms. Stryker is a director of medical equipment company Stryker Corp. She owns 6 percent of the company and serves on the board.
234. John Brown: $4.5 billion
Mr. Brown ran Stryker Corp. for 32 years.
317. Jon Stryker: $3.5 billion
Mr. Stryker inherited a stake in Stryker Corp. He is an architect and LGBTQ activist.
380. Stewart Rahr: $2.8 billion
Mr. Rahr expanded his father’s pharmaceutical company, Kinray, before selling it to Cardinal Health in 2010.
388. Pat Stryker: $2.7 billion
Ms. Stryker inherited a stake in Stryker Corp. and is a philanthropist.
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