Carnosic acid, a chemical found in the herb rosemary, has shown promising effects on protecting retinal cells against oxidation thanks to its antioxidant and anti-inflammatory activity, according to a study published in the medical journal Investigative Ophthalmology and Visual Science.
The study, conducted by an author in La Jolla, Calif., tested the chemical on retina derived cell lines as well as on dark-adapted rats given intraperitoneal injections of carnosic acid before exposing them to white light. Researchers studied the damage done to the cells by measuring the outer nuclear layer thickness and by electroretinogram.
The results showed the chemical did help protect the cells both in vitro and in vivo, offering possible clinical applications for diseases of the outer retina, such as age-related macular degeneration and retinitis pigmentosa, by protecting the cells from oxidative stress.
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The study, conducted by an author in La Jolla, Calif., tested the chemical on retina derived cell lines as well as on dark-adapted rats given intraperitoneal injections of carnosic acid before exposing them to white light. Researchers studied the damage done to the cells by measuring the outer nuclear layer thickness and by electroretinogram.
The results showed the chemical did help protect the cells both in vitro and in vivo, offering possible clinical applications for diseases of the outer retina, such as age-related macular degeneration and retinitis pigmentosa, by protecting the cells from oxidative stress.
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