The guideline, published in Gastroenterology, found only three clinical scenarios where probiotics were beneficial to patients; but in general, there was not enough evidence to support the use of probiotics for most conditions.
Probiotics should be used in the following settings:
- To prevent C. difficile infections in adult and children taking antibiotics.
- To prevent necrotizing enterocolitis in preterm, low birthweight infants.
- To manage pouchitis.
AGA doesn’t recommend probiotics for the treatment of Crohn’s disease, ulcerative colitis, irritable bowel syndrome and general C. difficile infection.
The guideline is available here.
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