Midatech completes preclinical cancer program — 4 insights

Midatech Pharma completed the preclinical program for its wholly-owned, advanced liver cancer candidate MTD119.

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Here’s what you should know:

1. The candidate was tested on “three subcutaneous or orthotopic liver cancer xenograft models treated with the active cytotoxic compound maytansine conjugated with Midatech’s gold nanoparticle technology.”

2. The candidate had anti-tumor properties in all models. In some models tumor growth was reduced more than six-fold. However, the mean reduction throughout all three models was three-fold.

3. MTD119 targets advanced hepatocellular carcinoma.

4. Midatech is beginning its formal investigation process now. The company expects to submit an application to the FDA for its first clinical studies in 2018.

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