Perioperative High Inspired Oxygen Therapy Does Not Prevent SSIs

Perioperative high inspired oxygen therapy was not found to be beneficial in preventing surgical site infection, according to a study published in Anesthesia & Analgesia.

The researchers investigated the clinical role of hyperoxia for preventing surgical site infection because of the disparate results previously reported on the topic. The objective in the study was to determine whether perioperative hyperoxia reduces surgical site infection.

The researchers conducted an electronic search using the National Library of Medicine's MEDLINE, Cochrane Collaboration's CENTRAL and EMBASE databases. The study found that the therapy was overall not beneficial, though positive results of two subgroup analyses (general anesthesia and colorectal surgery trials) suggest a benefit for hyperoxia in decreasing surgical site infections.

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