Study identifies 3 risk factors of postoperative endoscopic Crohn’s disease recurrence

Male sex, active smoking and previous intestinal resection are risk factors for postoperative endoscopic recurrence of Crohn’s disease, according to a study in Alimentary Pharmacology and Therapeutics.

Advertisement

Here are four things to know:

1. Between September 2010 and September 2017, researchers conducted a study of 289 Crohn’s disease patients at nine French academic medical centers. Study authors collected data at the time of surgery and between six and 12 months postoperatively during endoscopy procedures. 

2. Endoscopy within one year following surgery was performed in 78 percent of patients, and 32 percent of patients were active smokers at surgery. More than half — 63 percent — of patients received at least one anti-tumor necrosis factor therapy preoperatively.

3. After surgery, 18 percent of patients received thiopurines, and 29 percent received an anti-TNF agent. Endoscopic recurrence occurred in 47 percent of patients. 

4. Male sex, active smoking at surgery and previous resection were associated with a higher risk of endoscopic recurrence, while postoperative anti-TNF treatment was associated with a lower risk. 

More articles on gastroenterology:
GI leader to know: Dr. Juanita Merchant of the University of Arizona
Additional research needed in IBD stool therapy, AGA says
IU receives $3.1M NCI grant for computer-simulated CRC treatment research: 3 details

At the Becker’s 32nd Annual Meeting: The Business and Operations of ASCs, taking place October 29-31 in Chicago, ASC leaders, surgeons and healthcare executives will explore strategies to drive growth, enhance operational performance, navigate reimbursement challenges and prepare for the future of ambulatory surgery. Apply for complimentary registration now.

Register to Attend Webinar

Building a High-Performance Cardiac PET Program: What Health Systems Should Consider

Thursday, July 30
12:00 PM - 1:00 PM CDT

Presenters: Rupa Sanghani, MD, FACC, FASNC, Rush University Medical CenterBrendon Loiselle, CDL Nuclear Technologies

Advertisement

Next Up in GI & Endoscopy

Advertisement

Comments are closed.