Here are four things to know.
1. The study authors aimed to compare the cost-effectiveness of CT colonography and colonoscopy screening by using data on unit costs and participation rates from a randomized controlled screening trial in a dedicated screening setting.
2. The authors used observed participation rates and screening costs from the Colonoscopy or Colonography for Screening trial in a microsimulation model to estimate costs and quality-adjusted life-years gained with colonoscopy and CT colonography screening.
3. The participation rates for colonoscopy and CT colonography were 21.5 percent —1,276 of 5,924 trial participants — and 33.6 percent — 982 of 2,920 participants —respectively.
4. Colonoscopy was more cost-effective in screening strategies with one or two lifetime screenings. CT colonography was more cost-effective in strategies with more lifetime screenings.
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