ACG issues guidelines for C. difficile infection

The American College of Gastroenterology shared new clinical guidelines for Clostridioides difficile infections, which cause inflammation of the colon and diarrhea.

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The new guidelines propose an algorithm for testing for C. difficile infections and address best practices around fecal microbiota transplantation in recurrent and severe cases, according to a May 19 news release.

“FMT has emerged as an effective treatment, but questions remain about best methods of delivery, optimal donor screening, and long-term safety of the procedure,” the guideline authors noted.

The guideline also recommends against probiotics as a primary prevention method for C. difficile infections. It reviews evidence for management approaches in patients who are pregnant, lactating, immunocompromised or who have inflammatory bowel disease.

Access the guideline published in The American Journal of Gastroenterology here.

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