Gastroenterology is increasingly shifting to the outpatient setting, with physician groups and private equity platforms building large networks of ambulatory surgery centers. In 2025, a handful of GI organizations stand out for their growing ASC portfolios.
Here are five GI companies to know, by ASC footprint, this year:
- U.S. Digestive Health: Exton, Pa.-based U.S. Digestive Health, acquired by Optum’s SCA Health in early 2025, operates one of the largest GI ASC portfolios in the country. The platform includes 24 ASCs, 40 practice sites and more than 250 providers across Pennsylvania and surrounding states.
The Optum acquisition was among the biggest GI transactions of the year and positioned USDH as a key player in ASC-based digestive care.
- GI Alliance: GI Alliance, based in Southlake, Texas, remains the largest GI platform in the U.S., with more than 1,000 physicians across more than 400 sites in 20 states. Its ASC footprint includes dozens of centers nationally, supported by strategic partnerships and acquisitions.
Backed by Apollo Hybrid Value Fund, GI Alliance received a major boost in late 2024 when Cardinal Health acquired a $2.8 billion majority stake, giving it additional scale and resources to expand its ASC presence.
- Gastro Health: Miami-based Gastro Health operates over 150 locations and more than 400 physicians, with a strong ASC and endoscopy center presence in Florida, Ohio and Virginia.
The group, backed by Omers Private Equity, has made ASC expansion central to its growth model, emphasizing joint ventures and de novo development in competitive urban and suburban markets.
- United Digestive: United Digestive, headquartered in Atlanta, manages more than 80 practice locations with 129 physicians across the southeast U.S. Its model is heavily ASC-focused, with a growing network of GI surgery centers developed through partnerships and acquisitions.
The group, backed by Kohlberg & Co., has leaned on ASC joint ventures to expand its reach in Georgia and beyond.
- Allied Digestive Health: Based in West Long Branch, N.J., Allied Digestive Health includes more than 200 providers across dozens of sites in New Jersey. The group was formed in 2015 by the merger of five practices and is backed by Assured Healthcare Partners.
Its ASC footprint in New Jersey has steadily expanded, with affiliated endoscopy centers serving as the backbone of its regional care model.
Together, these organizations operate dozens of GI ASCs nationwide, reflecting the specialty’s shift toward lower-cost, outpatient settings — and signaling that ASC growth remains central to GI consolidation in 2025.
