Study researchers conducted a systematic review and meta-analysis of 51 trials from January 2000 to March 2017. Researchers selected randomized trials comparing manipulation and mobilization therapies. There were no treatments, other active therapies or multimodal therapeutic approaches.
Nine trials comprising 1,179 patients provided a sufficient amount of data and were similar enough to be included in the meta-analysis.
Researchers found manipulation significantly reduced pain and disability when compared to other active comparators. Mobilization significantly reduced pain, but did not reduce disability when assessing other active comparators.
Researchers concluded, “There is moderate-quality evidence that manipulation and mobilization are likely to reduce pain and improve function for patients with chronic low back pain; manipulation appears to produce a larger effect than mobilization. Both therapies appear safe. Multimodal programs may be a promising option.”
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