Study: Diabetes Might Start in the Intestine

Research conducted by scientists at the Washington University School of Medicine in St. Louis suggests problems controlling blood sugar might begin in the intestines, according to a university news release.

Previous studies have focused on the pancreas, where insulin is produced, and the liver, where sugar is stored. In this study, researchers studied mice that are unable to make fatty acid synthase, an enzyme crucial for lipid production and regulated by insulin. People with diabetes have defects in FAS production. Mice without the enzyme in the intestines developed chronic inflammation in the gut, a predictor of diabetes.

The study was published in Cell Host & Microbe.

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