Study: Acid Reflux Drugs May Increase Risk of C. Difficile

Acid reflux drugs such as Aciphex and Nexium have been linked to heightened risk of diarrhea caused by Clostridium difficile, according to a Third Age report.

The research, presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy, found that patients taking proton pump inhibitors were more than three times as likely as others to develop diarrhea caused by C. diff.


The theory behind the findings is that PPIs decrease acidity in the stomach, allowing C. diff. to survive longer.


Related Articles on Proton Pump Inhibitors:

Study: Even Low-Dose Aspirin Raises GI Bleeding Risk

Study: Infants' GERD Symptoms Do Not Improve From Proton-Pump Inhibitors

Study: Multipolar Electrocoagulation With Acid Suppression Effective for Barrett's Esophagus


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