Serrated polyposis syndrome patients have a higher risk of developing CRC: 4 things to know

Patients with serrated polyposis syndrome have an increased risk of colorectal cancer, according to study published in Gut.

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Here are four things to know:

1. Researchers examined 296 patients with serrated polyposis syndrome with a median follow-up time of 45 months — a median of 26 serrated polyps and three adenomas per patient were detected.

2. Forty-seven patients developed colorectal cancer at a mean age of 53.9 years, and four of the cases were detected during surveillance.

3. Patients with more than two sessile serrated adenomas/polyps proximal to splenic flexure and one or more proximal SSA/P with high-grade dysplasia were independent CRC risk factors.

4. Close colonoscopy surveillance shows a low risk of developing CRC — the risk decreases to 1.9 percent in five years.

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