Perioperative Atenolol Linked to Lower Mortality Rates Than Metroprolol

Perioperative beta-blockade using atenolol is associated with reduced mortality compared to metoprolol, according to a study published in Anesthesiology.

According to the study’s abstract, the Atenolol study of 1996 demonstrated that perioperative beta-blockade reduced post-surgical mortality. The current study tests whether a difference exists in mortality rates between patients receiving perioperative atenolol and metoprolol.

The study divided high-risk inpatients at San Francisco Veterans Affairs Medical Center since 1996 into two groups: patients who received perioperative atenolol only and patients who received metoprolol only. Propensity matching analysis was used to correct for differences in population risk factors.

The analysis showed that thirty-year mortality and one-year mortality was less likely for patients receiving atenolol than those receiving metoprolol.

Read the abstract on the study in Anesthesiology.

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