Higher Zofran Dose May Cause Patient Heart Problems

The FDA released a safety communication for the drug Zofran, which could pre-dispose patients to develop a potentially fatal heart rhythm known as Torsades de Pointes, according to the American Society of Anesthesiologists.

Advertisement

Preliminary results from a clinical study of Zofran, or ondansetron, showed a 32 mg single intravenous dose may affect the electrical activity of the heart.

GlaxoSmithKline, the makers of Zofran, will change the drug label to remove the 32 mg single intravenous dose. The new label will suggest a lower intravenous dose, not to exceed 16 mg.

Zofran is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy and surgery.

More Articles on Anesthesia:
Southern Medical Association Names Anesthesiologist President
CareFusion Release Anesthesia Systems With More Patient Protections
Locale Anesthesia Conversion Factors Released From CMS

At the Becker’s 32nd Annual Meeting: The Business and Operations of ASCs, taking place October 29-31 in Chicago, ASC leaders, surgeons and healthcare executives will explore strategies to drive growth, enhance operational performance, navigate reimbursement challenges and prepare for the future of ambulatory surgery. Apply for complimentary registration now.

Advertisement

Next Up in Anesthesia

  • The Morgantown-based West Virginia University School of Nursing is increasing its Doctor of Nursing Practice Nurse Anesthetist program from 15…

Advertisement

Comments are closed.