Researchers found the presence of colorectal tumor tissue was markedly decreased in patients with colorectal polyps assigned to take allopurinol, according to the preliminary results of a study. Colorectal tumor tissue contain high levels of reactive oxygen metabolites that inhibit programmed cell death, which is a mechanism involved in cancer control. Researchers are continuing to test the effect of ROM scavengers, such as allopurinol, to measure their effects on chemoprevention.
Read the AACR news release about allopurinol.
Read other coverage about colorectal cancer:
– Researchers Urge for Revisions to Guidelines for Serrated Polyp Surveillance
– Large, Serrated Polyps Carry Greater Risk of Colorectal Cancer Than Other Factors
– Researchers Suggest Non-Steroidal Anti-Inflammatory Drugs Prevent Colon Cancer
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