Fibronectin is a naturally occurring protein that supports the survival, growth and communication of neurons in the brain and spinal cord. Researchers found an injection of fibronectin into the spinal cord triggers specific signaling pathways and inhibits the development of chronic pain.
While researchers don’t understand the exact mechanisms of the connection between fibronectin and pain relief, study results showed fibronectin maintained the integrity of the blood-spinal cord barrier and suppressed the inflammatory response. Researchers also found fibronectin reversed decreases in serotonin, which influences pain perception, due to spinal cord injury.
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