Researchers induced acute pancreatitis in mice and found the level of dendritic cells in the pancreas doubled. When the mice with depleted dendritic cell levels were induced with acute pancreatitis, they developed pancreatic necrosis and died within four days.
Researchers concluded high levels of dendritic cells can protect the pancreas from acute pancreatitis damage, and low levels of dendritic cells are associated with increased pancreas injury including pancreatic necrosis, complete pancreas cell and tissue death.
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