Study: New Strategies Necessary to Achieve Glycemic Control

New strategies should be developed to achieve glycemic control with a minimal risk of hypoglycemia, according to a report published in Anesthesiology.

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Postoperative status is associated with so-called stress induced hyperglycemia, defined as transient hyperglycemia in patients without previous evidence of diabetes mellitus. The adverse effects of hyperglycemia are undebatable, and data strongly supports that blood glucose concentration should be carefully controlled.

However, the concept of tight glucose control by intensive insulin therapy should be revisited, as several large randomized controlled trials have shown inconsistent results. Some trials revealed no effect, while others showed increased mortality in the glycemic control group. The authors recommend TGC should not be used in routine practice regardless of setting, type of patients and team education, and new strategies should be developed.

Read the Anesthesiology study on glycemic control.

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