Lower Dose of Dexamethasone Effective in Reducing Post-Operative Nausea

A study was conducted at Northwestern Memorial Hospital in Chicago to establish an optimal dose for dexamethasone, a drug used to decrease post-operative nausea and vomiting caused by anesthesia, according to Anesthesia-Analgesia.

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The study compared the use of 4 mg to 5 mg and 8 mg to 10 mg intravenous doses. A total of 6,696 subjects were a part of 60 randomized clinical trials.

Results showed a similar effect with the 4 to 5 mg dose as the 8 to 10 mg dose, which supports using the lower dosage to get the same antiemetic properties.

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