FDA Rejects New AstraZeneca Peptic Ulcer Drug

The U.S. Food and Drug Administration sent AstraZeneca a Complete Response Letter, rejecting a new drug application for the company’s Axanum, according to an AstraZeneca news release.

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Axanum is a fixed-dose combination containing low-dose acetylsalicylic acid and the active ingredient of Nexium for the prevention of cardio- and cerebrovascular events in patients requiring continuous low-dose ASA treatment and at risk for developing ASA associated gastric and/or duodenal ulcers. The company is currently in discussions with the FDA regarding next steps for the drug, according to the release.

The FDA also rejected a supplemental new drug for Nexium, which was submitted for the risk reduction of low-dose aspirin-associated peptic ulcers.

Read the release on AstraZeneca’s CRLs for Axanum and Nexium.

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