6 Things to Know About Ulcerative Colitis, Crohn’s Disease & Cancer Risk

Researchers conducted a population-based cohort study of the risk of gastrointestinal and extraintestinal cancers in relation to Crohn’s disease and ulcerative colitis. The results were published in the journal Clinical Gastroenterology and Hepatology.

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•    772 cases of cancer occurred in a group of 13,756 Crohn’s disease patients.
•    2,331 cases of invasive cancer occurred in a group of 35,152 patients with ulcerative colitis.
•    Crohn’s disease was weakly associated with gastrointestinal cancers and extraintestinal cancers.
•    Hematologic malignancies, smoking-related cancers and melanoma were the most strongly associated cancers in Crohn’s disease.
•    Association between ulcerative colitis and gastrointestinal and extraintestinal cancers were weaker than in Crohn’s disease.
•    The risk of gastrointestinal cancer in IBD patients decreased over time, while the risk of extraintestinal cancer remained relatively stable.

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