Participants included 139 patients who underwent thermal, pressure and ischemic experimental pain testing before and after administration of morphine and butorphanol. Based on the results, researchers established four distinct drug response profiles. Three drug profiles showed excellent analgesic efficacy produced by one type of opioid on one pain stimulus modality. However, the fourth drug response profile only showed average analgesic efficacy across all pain modalities for both opioids.
Read the abstract about drug response profiles.
Read other coverage about pain management:
– Florida Society of Pain Management Providers Sets Record Straight About PDMP
– Opioid Use in Early Pregnancy Linked to Birth Defects
– FDA Approves Pain Treatment Ofirmev
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