Researchers looked at muscle relaxants — including benzodiazepine agents diazepam and triazolam and non- benzodiazepine agent zopiclone — and found they did not reduce pain when taken for up to two weeks, but use was associated with drowsiness and dizziness. They also looked at neuromodulators — including oral nefopam, topical capsaicin and oromucosal cannabis — and found weak evidence to support pain reduction. Use was associated with nausea, sweating, dizziness, dry mouth, light headedness, local burning and irritation.
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