Academic Emergency Medicine study examines safety of opioid alternative

A new study published in Academic Emergency Medicine found ketamine in low doses was as effective as morphine for controlling acute pain, Medscape reported.

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The researchers included 261 patients across three randomized, controlled trials in their analysis.

Here’s what you need to know:

1. Intravenous ketamine was not inferior to intravenous morphine in terms of pain scale reduction in a patient-level data analysis.

2. The researchers said ketamine has a lesser risk of severe adverse reaction than morphine, but a greater risk of emergence phenomenon and dizziness.

3. There are adverse side effects for both drugs, the researchers said. Opioids are linked with vomiting, itching, nausea, low blood pressure, respiratory depression and hypoxia, along with the danger of misuse and addiction. Ketamine is also potentially addictive and is associated with symptoms in the lower urinary tract.

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