Which colonoscopy bowel prep is best? 5 study insights

A prospective study in The American Journal of Gastroenterology evaluated which colonoscopy bowel preps are best tolerated and most effective.

Five things to know:

1. The researchers featured patients aged 18 years and older who presented for an outpatient colonoscopy at a large medical center in the study. The study's primary outcome was bowel cleansing quality, which was measured by the Boston Bowel Preparation Scale.

2. Approximately 4,339 colonoscopies were performed by 75 endoscopists. Compared with GoLYTELY, the bowel preps Magnesium citrate, MiraLAX with Gatorade, MoviPrep, OsmoPrep, Prepopik/Clenpiq and Suprep all had significantly higher prep tolerability.

3. For bowel cleansing, Suprep, MoviPrep and MiraLAX with Gatorade had higher total Boston Bowel Preparation Scale scores compared with GoLYTELY. There were no significant differences among the other preps.

4. Split-prep dosing was associated with better cleansing.

5. Men, opioid and tricyclic antidepressant users and patients with diabetes and cirrhosis had worse cleansing overall.

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