UC San Diego researchers discover liver cancer development suppressor — 5 insights

UC San Diego researchers discovered that a synthetic double-stranded RNA, plC, can boost anti-tumor innate immune functions in developing liver cancer.

Here's what you should know:

1. Researchers believe the treatment could be developed into a vaccine to prevent cancer in high-risk individuals.

2. Researchers published their findings in Cell Reports.

3. By reprogramming macrophages and activating natural killer cells and dendritic cells, tumor development is suppressed.

4. Researchers tested plC on mice with liver cancer at several different stages. The greatest decrease in tumor numbers and size was at one month. At three months, the impact was reduced but significant, at five months with developed tumors, there was little effect.

5. Researchers are planning future studies to evaluate how plC reacts with other agents that stop cancer growth.

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