Study Compares Sodium Phosphate With Polyethylene Glycol in PillCam Colon Endoscopy

Researchers found that excluding sodium phosphate boosters in preparation for PillCam colon capsule endoscopy resulted in a “clinically meaningful reduction” in capsule excretion rates that were partially compensated by polyethylene glycol boosters, according to an article published in Journal of Clinical Gastroenterology.

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The study included 40 patients, 20 of whom were selected for a standard regimen of clear liquid diet, 4 L of polyethylene glycol and 1-2 sodium phosphate boosters. The other 20 patients were selected for a modified regimen that was similar to the standard regimen but replaced the sodium phosphate boosters with 1-2 polyethylene glycol boosters. All 40 patients underwent colon capsule endoscopy, and researchers measured excretion rate, colon transit time, colon cleansing and accuracy.

Results showed 100 percent and 75 percent of colon capsule endoscopies were excreted in the standard and modified regimen, respectively. The standard and modified group experienced colonic transit times of 2.17±1.43 hours and 5.32±2.53 hours, respectively Sensitivity and specificity for ≥6-mm polyps were 63 percent and 87 percent for the standard regimen and modified regimen groups, respectively.

Read the study about colon capsule endoscopy.

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