Researchers analyzed data from the Cancer Incidence in Five Continents dataset and other supplemental sources to report on worldwide CRC incidence rates between 2008 and 2012.
Researchers found:
1. Incidence rates increased in 19 countries in an under 50-year-old cohort. Nine of those countries decreased CRC incidence rate in an older cohort.
2. Early-onset CRC rates were stable in 14 of 36 countries.
3. Rates decreased in Austria, Italy and Lithuania.
4. Young adults in Cyprus, the Netherlands and Norway saw a twice-as-rapid increase when compared to older adults.
5. In most high-income countries, early-onset CRC rates only started increasing in the mid-1990s.
Researchers concluded, “CRC incidence increased exclusively in young adults in nine high-income countries spanning three continents, potentially signalling changes in early-life exposures that influence large bowel carcinogenesis.”
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