Early-onset CRC rates still on the rise in most countries — 5 insights

Early-onset colorectal cancer rates continue to increase globally, according to a study published in Gut.

Researchers analyzed data from the Cancer Incidence in Five Continents dataset and other supplemental sources to report on worldwide CRC incidence rates between 2008 and 2012.

Researchers found:

1. Incidence rates increased in 19 countries in an under 50-year-old cohort. Nine of those countries decreased CRC incidence rate in an older cohort.

2. Early-onset CRC rates were stable in 14 of 36 countries.

3. Rates decreased in Austria, Italy and Lithuania.

4. Young adults in Cyprus, the Netherlands and Norway saw a twice-as-rapid increase when compared to older adults.

5. In most high-income countries, early-onset CRC rates only started increasing in the mid-1990s.

Researchers concluded, "CRC incidence increased exclusively in young adults in nine high-income countries spanning three continents, potentially signalling changes in early-life exposures that influence large bowel carcinogenesis."

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