Researchers analyzed data from 175,912 women enrolled in the Nurses’ Health Study I in 1976 and the NHS II in 1989. Follow-up data from 2003 found 257 cases of Crohn’s disease and 313 cases of ulcerative colitis. Researches determined the multivariate-adjusted hazard ratio for women living in southern latitudes compared with those living in northern latitudes at age 30 was 0.48 for Crohn’s disease and 0.62 for ulcerative colitis. The association held even after researchers accounted for differences in self-reported ancestry, smoking and other environmental factors.
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