Delaying follow-up colonoscopy after positive FIT increases CRC risk — 4 study insights

A study published in Clinical Gastroenterology and Hepatology examined how follow-up colonoscopy time after positive fecal immunochemical testing affects colorectal cancer rate.

Researchers examined 39,346 patients who completed a colonoscopy more than a month after a positive FIT-result between 2004 and 2012. Researchers evaluated the CRC incidence rate.

Here's what they found:

1. About 2,003 patients had CRC and 445 patients had advanced-stage CRC.

2. Researchers found when patients delayed the follow-up colonoscopy for more than six months, their risks were significantly higher.

3. The risks continued escalating if the follow-up colonoscopy was delayed for more than 12 months.

4. However, there was no significant increase in risk if the follow-up was done between three months and six months.

Researchers concluded, "We found that among patients with positive results from a FIT, risks of CRC and advanced-stage disease increase with time. These findings indicate the importance of timely colonoscopy after a positive result from a FIT."

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