Colorectal Cancer Alliance awards $625K to fund CRC research — 6 insights

Eric Oliver - Print  |

The Colorectal Cancer Alliance is providing four researchers a combined $625,000 in grants to fund CRC research.

What you should know:

1. The Alliance is funding four separate projects; three relate to early-onset CRC and one on personalized treatment options for rectal cancer patients.

2. New York City-based Memorial Sloan Kettering Cancer Center's J. Joshua Smith, MD, PhD, will use the funds to advance past research on patient-specific rectal cancer organoids, including growing human-specific rectal cancer models in mice to develop and test personalized treatments.

3. Memorial Sloan's Robin B. Mendelson, MD, will examine the gut microbiome of patients under 50, and compare it to microbiomes of older patients with CRC and microbiomes of young, healthy people.

4. Philadelphia-based Fox Chase Cancer Center's Joshua Meyer, MD, will describe the genetic and genomic features of CRC patients, and characterize early-onset CRC patients' biology.

5. New Haven, Conn.-based Yale School of Medicine's Rosa Maria Munoz Xicola, PhD, will examine how the adenomatous polyposis coli-negative subset of CRCs develop, and whether the APC-negative subset disproportionately impacts African Americans and/or young people.

6. The Alliance aims to invest $10 million in CRC research projects.

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