The lifetime risk of heart failure in the U.S. has climbed to 24% — about 1 in 4 people, according to the Heart Failure Society of America’s “HF Stats 2025: Heart Failure Epidemiology and Outcomes Statistics” report. Moreover, estimates project U.S. heart failure expenses could grow from $32 billion in 2020 to as much as $142 billion by 2050.
Currently, 6.7 million Americans live with the condition, a number expected to grow to 8.7 million by 2030. Heart failure contributed to more than 425,000 deaths in 2022 and accounted for nearly half of all cardiovascular deaths, according to a Sept. 22 system news release.
The report highlights major disparities, noting Black Americans experience the highest incidence and mortality rates. It also noted that fewer than 1 in 4 eligible patients with reduced ejection fraction are receiving full guideline-directed therapy — a gap that, if closed, could save an estimated 1.19 million lives annually worldwide.
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