Study: Hydrogen Peroxide Vapor Beats Standard Disinfection for Multidrug-Resistant Organisms

Acquiring a multidrug-resistant organism from a room previously occupied by a patient with MDRO is less likely when the room was disinfected with hydrogen peroxide vapor than with standard methods, according to a study in Clinical Infectious Diseases.

Researchers studied MDROs on six high-risk units in a 994-bed tertiary care hospital. On three units, hydrogen peroxide vapor was used to decontaminate rooms that were previously occupied by patients infected or colonized with epidemiologically important MDROs. Standard methods were used to disinfect these types of rooms on the remaining three units.


Patients in rooms that were decontaminated with hydrogen peroxide vapor were 64 percent less likely to acquire any MDRO and 80 percent less likely to acquire vancomycin-resistant enterococci than patients in rooms cleaned by standard methods. In addition, decontamination with hydrogen peroxide vapor decreased the proportion of rooms environmentally contaminated with MDROs. 

More Articles on Infection Control:

Study: Cleaning With Hydrogen Peroxide Vapor Linked to Lower C. Diff-Associated Diarrhea Rates
6 Strategies to Prevent Multidrug-Resistant Organism Outbreaks

Study: Disinfection Cap Decreased CLABSIs by 52%

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