Study: Cleaning With Hydrogen Peroxide Vapor Linked to Lower C. Diff-Associated Diarrhea Rates

A hospital-wide, targeted terminal cleaning program using hydrogen peroxide vapor technology is associated with decreased rates of Clostridium difficile-associated diarrhea, according to a study in American Journal of Infection Control.

Researchers implemented a terminal cleaning program in a 900-bed community hospital. Before the program, January 2007 to November 2008, rooms used by patients with CDAD were cleaned via one or more rounds of bleach cleaning. Under the new program, January to December 2009, rooms used by CDAD patients were cleaned using bleach and HPV decontamination. If HPV decontamination was not possible the same day as the patient left the room, the hospital used four rounds of cleaning with bleach. 


Of 334 rooms vacated by patients with CDAD, 54 percent were cleaned with HPV decontamination. The rate of nosocomial CDAD decreased significantly from 0.88 cases per 1,000 patient days to 0.55 cases per 1,000 patient-days.

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