Study: Cefazolin Better Than Vancomycin for Infection Control in Dialysis Patients

A recent study published in the Journal of the American Society of Nephrology suggests cefazolin may be better at controlling infections than vancomycin in dialysis patients.


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Researchers compared the effectiveness of various antibiotics at preventing hospitalization and death from bloodstream infection. They reviewed more than 500,000 blood culture results from their chronic kidney disease database, looking for methicillin-sensitive strains of S. aureus bloodstream infection. They also identified when physicians used vancomycin or cefazolin to treat these infections.  

The researchers found patients treated with cefazolin experienced a 38 percent lower rate of hospitalization and death from bloodstream infections compared to patients treated with vancomycin. Cefazolin-treated patients also had a 48 percent lower rate of sepsis.

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