Proton Pump Inhibitors Correlated With Increased C. diff

 

Patients who used proton pump inhibitors, drugs used mostly to lower stomach acid production, were more likely to acquire C. diff infections, according to a new study published in the Journal of the American Medical Association.

 

Out of more than 1,000 patients surveyed, two-thirds had used antibiotics in the last three months, and more than one-quarter reported using proton pump inhibitors recently. Use of proton pump inhibitors was more common among those who had not used antibiotics recently.

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Researchers concluded that while most C. diff infection prevention happens through reduced antibiotic use and better outpatient infection control practices, curtailing proton pump inhibitor usage could reduce C diff infections somewhat, by about 11 percent. 

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