Opioid-Related Adverse Events Associated With $1k Increase in Hospital Costs

Opioid-related adverse events are associated with more than a $1,000 increase in hospitalization cost and more than a day increase in length of hospital stay, according to research presented at the 2011 Midyear Clinical Meeting of the American Society of Health-Systems Pharmacists in New Orleans.

For their study, researchers analyzed data from 381 U.S. hospitals and identified adult patients who underwent common soft tissue and orthopedic surgical procedures and received opioids from Sept. 2008-Aug. 2010. The researchers found approximately 20 percent of the surgical patients experienced an opioid-related adverse event, which includes nausea, vomiting and constipation.


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The researchers also found patients who experienced an opioid-related adverse event had a 1.1-day increase in mean length of stay and a $1,028 mean increase from the baseline hospitalization cost compared to patients who did not experience an opioid-related adverse event.

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