5 Predictors of Infection From Antibiotic-Resistant Strain of E. Coli

Escherichia coli sequence type ST131, an antibiotic-resistant strain of E. coli, is associated with long-term care facilities and older patients, according to a study in Infection Control and Hospital Epidemiology.

Researchers analyzed extraintestinal E. coli isolates from healthcare settings in Olmsted County, Minn., that were submitted to laboratories in February and March 2011. They found several predictors of ST131 carriage:


•    Older age. ST131 accounted for 50 percent of E. coli isolates from patients aged 91 to 100, compared with 26 percent of isolates from patients aged 51 to 60 and 5 percent of isolates from patients aged 11 to 20.
•    Long-term care facility residence. ST131 accounted for 76 percent of isolates from LTCF residents.
•    Previous urinary tract infection.
•    High-complexity infection.
•    Previous use of fluoroquinolones, macrolides and extended-spectrum cephalosporins.

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