Patient Safety Tool: MRSA Evaluation and Treatment Guide

The Centers for Disease Control and Prevention has created a guide to help healthcare professionals working in the outpatient setting evaluate and treat MRSA infections.

According to the CDC, incision and drainage is the primary therapy for MRSA infections. Empiric antimicrobial coverage for MRSA may be warranted in addition to incision and drainage based on clinical assessment. Antibiotic treatment, if indicated, should be guided by the susceptibility profile of the organism. Obtaining specimens for culture and susceptibility testing is useful to guide therapy, particularly for those with more severe infections and those who fail to respond adequately to initial management.

MRSA skin infections can develop into more serious infections. It is important to discuss a follow-up plan with patients in case they develop systemic symptoms or worsening local symptoms or if symptoms do not improve within 48 hours.

To download the document, click here (pdf).

Download other patient safety-related tools and resources:


- Surgical Safety Checklist and Toolkit for Download From BCBS

- Sample Infection Control Risk Assessment

- Sample Sterile Processing Department Testing and Load Form and QI Worksheet

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