Study: Effective Propofol Dose Lower for Obese Children

The effective dose of propofol is lower for obese than non-obese children, according to a study presented at the annual meeting of the American Society of Anesthesiologists in Chicago and reported in Doctors Lounge.

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Olutoyin A. Olutoye, MD, from the Texas Children’s Hospital in Houston, and colleagues examined the ED95 of propofol for loss of consciousness in 40 obese and 40 non-obese children who presented for surgical procedures. The obese children had significantly lower ED95 of propofol compared to non-obese children, meaning they lost consciousness more quickly than their non-obese counterparts.

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