According to the study’s abstract, periprostatic nerve block is the standard anesthesia for ultrasound-guided transrectal prostate biopsy, but periprostatic infiltration creates a major source of discomfort for patients. Non-infiltrative anesthesia therefore presents an attractive alternative to periprostatic infiltration.
The researchers aimed to determine the effectiveness and safety of perianal-interrectal lidocaine gel, lidocaine-ketorolac gel and lidocaine-prilocaine cream in relieving pain. Three-hundred consecutive patients scheduled for US-guided TPB were randomized to receive one of the treatments.
The study found that lidocaine-prilocaine cream was most effective on probe-related pain, whereas lidocaine-ketorolac gel was most effective on sampling-related pain.
Read the abstract in UroToday on the study on non-infiltrative anesthetics.
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