The researchers developed and tested a new “pressurized olfactory device” in experimental animals. The researchers believe a similar technique used in humans might provide an effective, non-invasive technique for opioid drug administration.
The researchers designed the POD to deliver morphine or other drugs directly to the olfactory region of the nasal cavity. This region is small and difficult to reach, making up no more than 10 percent of the surface area of the human nasal cavity. It can only be accessed through a one- to two-millimeter slit in the back of the nasal cavity.
Experiments in rates demonstrated enhanced effects of morphine delivered through the POD.
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