Methylphenidate Induces Emergence from General Anesthesia, Study Says

A study published in the May issue of Anesthesiology found that methylphenidate enables rats to wake more quickly following a single dose of propofol and also induces emergence during continuous propofol.

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Taryn Tawoda

Researchers found that all six adult rats receiving continuous propofol promptly showed signs of arousal after methylphenidate, while none of the rats showed signs of movement following an injection of normal saline.

Further study is needed to determine if methylphenidate has the same effects on humans under propofol general anesthesia.

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