A recent surgical trial conducted over two year with 1,386 patients found no reduction in surgical site infection with the use of 80 percent inspiratory oxygen. However, the oxygen was associated with significantly increase long-term mortality, which was statistically significant in patients undergoing cancer surgery.
One hundred fifty-nine of 685 patients, or 23.2 percent, died in the 80 percent oxygen group, compared to 128 of 701, or 18.3 percent, assigned to 30 percent oxygen.
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