10 most commonly prescribed pain medications 

Hydrocodone-acetaminophen was the most commonly prescribed pain medication in 2022, according to a recent report from Definitive Healthcare. 

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Here are the top 10 pain medications prescribed in 2022, according to Definitive Healthcare. 

  1. Hydrocodone-acetaminophen
  2. Ibuprofen
  3. Tramadol
  4. Oxycodone-acetaminophen
  5. Oxycodone 
  6. Aspirin 
  7. Acetaminophen-codeine
  8. Morphine sulfate
  9. Butalbital-acetaminophen-caffe
  10. Acetaminophen
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