2025’s 10 richest healthcare billionaires 

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In Forbes‘ World’s Billionaires list, released April 1, highlights the world’s wealthiest individuals.

Below is a breakdown of the 10 richest U.S.-based healthcare billionaires featured among Forbes’ 3,028 global entries.

Note: The list is based on stock prices and exchange rates from March 7.

73. Thomas Frist Jr., MD, and family: $27 billion

Dr. Frist co-founded Nashville, Tenn.-based HCA Healthcare with his father in 1968.

199. Robert Duggan: $12 billion

Mr. Duggan is a biotech entrepreneur best known for leading the 2015 sale of Pharmacyclics, a cancer drug company, to AbbVie for $21 billion.

248. Carl Cook: $10.6 billion
As CEO and owner of Cook Group, Mr. Cook oversees a major medical device manufacturer based in Bloomington, Ind. The company was co-founded by his parents in the 1960s and remains family-owned.

347. Ronda Stryker: $8.6 billion
Ms. Stryker is a director at Stryker Corp., the medical technology firm founded by her grandfather, Homer Stryker, MD. She holds a significant ownership stake and plays an active role in the company’s governance.

369. John Brown: $8.2 billion
Mr. Brown served as CEO of Stryker Corp. for more than 30 years and later became chair emeritus. He remains closely tied to the company’s legacy.

487. Reinhold Schmieding: $6.9 billion
Mr. Schmieding is the founder of Arthrex, a Naples, Fla.-based company specializing in minimally invasive surgical technology. He launched the business in 1981 and continues to lead its operations.

597. Patrick Soon-Shiong, MD: $5.9 billion
Dr. Soon-Shiong is the inventor of Abraxane, a chemotherapy drug for pancreatic cancer. His pharmaceutical ventures have made him one of the most recognized figures in biotech.

634. Jon Stryker: $5.6 billion
Mr. Stryker is a philanthropist and founder of the Arcus Foundation, which supports LGBTQ+ and environmental causes. He is the grandson of Stryker Corp. founder Dr. Homer Stryker and inherited a significant stake in the company.

650. Li Ge, PhD: $5.4 billion
Dr. Ge co-founded WuXi AppTec, a global provider of R&D and manufacturing services for the pharmaceutical and biotech industries. He continues to serve as chairman and CEO.

887. Pat Stryker: $4.1 billion
Ms. Stryker is a philanthropist and founder of the Bohemian Foundation, which supports programs in music, community development, civic engagement, and global impact. She is also an heir to the Stryker Corp. fortune.

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