For their study, researchers analyzed cases from the Childhood Cancer Survivor Study, which is a study of 14,358 childhood cancer survivors who were diagnosed from 1970-1986. Randomly selected siblings served as controls, and upper GI, hepatic and lower GI adverse outcomes were assessed.
Researchers found survivors were at increased risk of late-onset complications of the upper GI tract, liver and lower GI tract, compared to their siblings. Factor contributing to increased risk of certain GI complications were older age at diagnosis, intensified therapy, abdominal radiation and abdominal surgery.
Read the study about GI complications among childhood cancer survivors.
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