H pylori infection eradication could lower gastric cancer risk: 3 insights

Eradicating Helicobacter pylori infection may reduce the indidence of gastric cancer, according to a study published in Gastroenterology.

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Researchers searched PubMed, Cochrane Library and ClinicalTrials.gov and reviewed titles and abstracts of studies to investigate the eradication of H pylori infection and its effect on gastric cancer risk. Twenty-four studies were included in the meta-analysis.

Here are three insights:

1. After adjustment for baseline gastric cancer incidence, individuals with eradication of H pylori infection were found to have a lower incidence of gastric cancer than those who did not receive eradication therapy.

2. H pylori infection eradication proved to have a significant benefit for asymptomatic infected individuals and individuals after endoscopic resection of gastric cancers.

3. The benefits of H pylori eradication did not differ with study design, sex or follow-up period.

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