No increased prevalence of microscopic colitis in IBS patients — 4 points

In a study published in Clinical Gastroenterology and Hepatology, researchers did not observe increased prevalence of microscopic colitis among irritable bowel syndrome patients versus other patients with diarrhea undergoing colonoscopy.

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Alexander C. Ford, MD, from the Leeds Gastroenterology Institute at St. James University Hospital in the United Kingdom, and colleagues searched relevant literature for cross-sectional surveys or case-control studies. They included 10 in their analysis.

Here are four points:

1. The pooled prevalence of IBS in patients with microscopic colitis was 33.4 percent, but it was not significantly higher in patients with microscopic colitis versus those without.

2. In three cross-sectional surveys, the pooled odds ratios for microscopic colitis in patients with IBS versus those without IBS was 0.68.

3. In four case-control studies, the odds ratios for microscopic colitis among patients with IBS versus patients without IBS was 5.16.

4. In conclusion, the data shows that one in three patients with microscopic colitis report IBS symptoms, but IBS symptoms were not more common in patients with microscopic colitis compared with individuals without microscopic colitis.

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